Astaxanthin is an all-natural extract that has been refined. According to medical certif ication, those harmful trace elements have been removed in the extraction process, so there are no side effects from long-term use. But only if you choose the right astaxanthin product. When we take astaxanthin, we should pay attention to our diet. We can't eat spicy food, and we should also pay attention to avoid smoking and staying up late.