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Supreme Fucoidan
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Supreme Fucoidan

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I.Supreme fucoidan and cancer

Many studies have confirmed that alginose gum has obvious inhibitory effect on colon cancer, breast cancer, liver cancer and leukemia, and can induce cell apoptosis, and has no adverse effects on normal cells, but the specific mechanism of action has not been clarified. It can be seen that adjuvant therapy for cancer can play a certain role.

II. Supreme fucoidan benefits

i. Beneficial for colorectal cancer (colon cancer)

Colorectal cancer is one of the top three most common cancers. It is estimated that there are about 1.2 million new cancer cases and more than 630,000 cancer deaths every year, accounting for nearly 8 percent of all cancer deaths. Despite the availability of many methods of cancer detection, the overall long-term prognosis for patients undergoing surgical resection has not changed significantly over the past decade, with a five-year survival rate of about 60% and more than half of colorectal cancers still being diagnosed only when regional or distant sites are involved.

A prospective, randomized, double-blind, controlled trials (6 months in 60 patients with metastatic colorectal cancer), showed that compared with control group using chemical target therapy alone, such as in chemotherapy with small molecular alginic sugar gum (4 grams each time, twice a day) can improve disease control rate. However, there was no significant improvement in other measures (such as overall response rate (ORR), survival without deterioration (PFS), overall survival (OS), adverse reactions (AEs), and quality of life (QOL)).

Conclusion: For patients with metastatic colorectal cancer, the adjuvant use of alginose gum in addition to targeted therapy may improve the disease control rate


ii. Help to lose weight and improve obesity

Obesity (meaning body mass index (BMI) greater than 30 kg/m2) has a wide range of effects on the body's systems, including lipid disorders, hypertension, sleep disordered breathing, diabetes, metabolic syndrome, non-alcoholic fatty liver disease, and orthopedic diseases.

Around the world, obesity-related deaths are expected to soon surpass those related to tobacco abuse.

Due to these comorbidities, the medical costs directly related to obesity are difficult to determine, but a conservative estimate of the medical burden is approximately US $150 billion per year. One animal study (in mice with food-borne obesity) found that alginate supplementation reduced body weight, food utilization, liver and epididymal fat relative quality, triglycerides, total cholesterol, and LDL levels.

Conclusion: Animal experiments showed that alginose gum may have positive effects on obesity, but it still needs to be further verified in human experiments


iii. Increase the protective efficacy of influenza vaccine after vaccination

Influenza virus infections cause as many as 430,000 hospitalizations and 20,000 to 40,000 deaths each year in the United States, with more than 90 percent of deaths occurring in older age groups.

As an individual ages, immune senescence leads to an increased susceptibility to infection, with higher morbidity and mortality compared to younger people.

Immune aging not only compromises the ability to protect against infection, but also reduces the protection after vaccination. A randomized, placebo-controlled, double-blind study (24 weeks of 70 older adults who received influenza vaccine) found that, compared with a placebo, Oral alginose significantly increases antibody titers and natural killer cell activity after vaccination.

Conclusion: For the immunocompromised elderly, the intake of alginose gum can increase the production of antibodies after vaccination, which may have a positive effect on the prevention of influenza.


iv. Improve skin damage caused by photoaging

Among the many factors, ultraviolet light is the most well-known external factor that promotes skin aging, also known as photoaging.

Photoaging is a process of premature skin aging characterized clinically by sunburn, wrinkles, loss of elasticity, dryness, pigmentation, and actinic keratosis, which is attributed to continuous and long-term exposure to ultraviolet radiation (including UVA and UVB) from the sun. Unlike sunburn and tanning reactions, which take several hours to several days to develop, Light aging takes decades.

An animal study showed that the ingestion of small molecular alginose gum significantly inhibited UV-induced wrinkle formation, skin edema, and neutrophil entry into photodamaged lesions, compared with a control group that did not ingest.

Conclusion: It was found in animal studies that small molecular alginose gum has a protective effect on light-induced skin aging, but it needs further verification in human studies


III. Supreme fucoidan dosage

As for the usage and dosage of alginose gum, you need to consult the relevant professional, because everyone's situation is different, there may be certain differences in the use of alginose gum. It is recommended to have a detailed understanding of the specific use method and dosage before purchase.

Fucoidan Extract cost -RealclearBio

IV. Supreme fucoidan health benefits

i. Anti-tumor, inhibit the growth of tumor blood vessels

Researchers have demonstrated that the antitumor activity of alginose gum is related to its ability to enhance the immune response. Alginose gum can inhibit the degradation of an enzyme in the extracellular matrix of the inner subcutaneous area, thus inhibiting tumor migration. The polysaccharides containing sulfate group or its degradation can induce apoptosis of cancer cells and can be used as inducer of apoptosis of cancer cells. But alginose gum has different effects on different tumors. There are, of course, individual differences.

Alginose gum can cut off the nutrient supply of the blood vessels near the tumor cells, so that the growth of tumor cells is inhibited, and the tumor cells naturally apoptosis because of the lack of nutrient supply. In this respect, the research in Japan is relatively in-depth, and alginose gum has been successfully applied in the treatment of cancer.


ii. Anticoagulation

Alginose gum has anticoagulant function, but there are different views on its coagulation mechanism in the research community. This function was made by experiment. In the experimental process, it was found that the higher the molecular weight of alginose gum, the stronger the inhibition of thrombin on the coagulation of fibrinogen, the lower the concentration of sulfate group, these activities also decreased. The anticoagulant mechanism of alginose gum remains to be further studied.


iii. Lowering blood lipids

Experts from Ocean University of China have done experiments to prove that brown alginose gum has the function of reducing blood lipid. Atherosclerosis is the main pathological basis of many cardiovascular and cerebrovascular diseases, and high lipid and lipid peroxide content are important factors leading to atherosclerosis. Therefore, reducing the content of lipid and high lipid peroxide is an important measure to prevent the occurrence of atherosclerosis. Alginose gum can reduce human blood fat. Therefore, for some obese groups can play a certain weight loss effect.


V. Supreme fucoidan hair growth

Alginose gum contains many vitamins and minerals essential for hair growth. Iron and zinc sustain hair growth. Zinc deficiency can cause hair loss. In addition, vitamin A and C are also needed to produce sebum, which acts as a natural conditioner; Vitamins B and E help keep hair healthy. Calcium, rich in seaweed, is another important mineral in hair production. Finally, detoxifying the body can promote healthier hair growth.


VI. Supreme fucoidan ingredients

Alginose gum is a kind of natural complex polysaccharide. It is a special polysaccharide that contains a natural sulfuric acid group at the end of its molecular chain. It is because of the existence of natural sulfuric acid group that alginate gum can show excellent and obvious physiological activity. Modern science has proved that alginose gum is not a single structure compound, but a family of compounds with different chemical components. contains

L-fucos-4-sulfate, a small amount of galactose, manna, sugar, sugar, uronic acid, arabinose and protein, etc.


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