English Views: 0 Author: Site Editor Publish Time: 2022-09-09 Origin: Site
The medicinal use of ganoderma lucidum has a history of more than 2,000 years in China, and has been regarded by successive medical experts as a magical treasure to nourish the strength and strengthen the foundation. In 2000, there were more than 100 species of Ganoderma fungi, the most widely distributed of which was G. Lu-cidum, followed by G.japonicum.
There are also tree tongue (g.applana-tum), pine ganoderma ganoderma (G.sugae) and bushu ganoderma (g.capense) which are used for medicinal purposes. Through a large number of clinical studies, ganoderma lucidum has different degrees of curative effect on neurasthenia, hyperlipidemia, coronary heart disease angina pectoris, arrhythmia, Keshan disease, plateau discomfort, hepatitis, hemorrhagic fever, dyspepsia, tracheitis and so on. 
It should be noted that only through the use of ganoderma lucidum diet therapy this method can not play an obvious prevention and control effect, it is suggested that the use of cassia, black oolong and other prescriptions for the traditional Chinese medicine decoction tea this classic tea, can play a good prevention and control effect on hyperlipidemia and other diseases. Pharmacological studies have proved that ganoderma lucidum has many biological activities.
Due to the amino acid, peptide, protein, fungal lysozyme, and carbohydrates (reducing sugars and polysaccharides), ergosterol, triterpenes, coumarin, volatile oil, stearic acid, benzoic acid, alkaloids, vitamin B2 and C; The spores also contain mannitol and Trehalose.
Ganoderma lucidum powder is light brown, brown to purplish brown. Hyphae scattered or clumped, colorless or light brown, slender, slightly curved, branched, 2.5 to 6.5 m in diameter. The spore is brown, ovate, apical truncate, the outer wall is colorless, the inner wall has verrucous protrusion, 8 ~ 12 micron long, 5 ~ 8 micron wide.
Take 2g ganoderma lucidum powder, add 30 ml ethanol, heat reflux for 30 minutes, filter, filtrate to dry, the residue add 2 ml methanol to dissolve, and serve as the test solution. Another 2g of ganoderma lucidum was used to prepare the solution. For TLC test, 4 μL of each of the above two solutions were absorbed and respectively placed on the same silica gel G thin layer plate. The upper solution of petroleum ether (60 ~ 90℃) -ethyl formate (15:5:1) was used as the developing agent. The solution was unfolded, removed, dried, and examined under ultraviolet lamp (365 nm). In the chromatogram of the test product, fluorescence spots of the same color were shown at the corresponding position with the chromatogram of the control medicinal material.
i. Protect liver and detoxify: Ganoderma lucidum has protective effect on liver injury caused by a variety of physical, chemical and biological factors. Whether before or after the occurrence of liver damage, taking ganoderma lucidum can protect the liver and reduce liver damage. Ganoderma lucidum still can promote liver to the metabolism of medicaments, toxicants, have exact curative effect to toxic hepatitis. Especially chronic hepatitis, Ganoderma lucidum can eliminate dizziness, fatigue, nausea, liver area discomfort and other symptoms, and can effectively improve liver function, make each index tends to normal. So, ganoderma lucidum can be used in the treatment of chronic poisoning, all kinds of chronic hepatitis, liver cirrhosis, liver dysfunction.
ii. Treatment of diabetes: The principle of ganoderma lucidum lowering blood glucose is to promote the use of sugar in the tissue. After taking Ganoderma lucidum, it can replace insulin to inhibit the release of fatty acids, and improve blood glucose, urine sugar and other symptoms. The water-soluble polysaccharide in Ganoderma lucidum can reduce the incidence of non-insulin dependent diabetes mellitus.
iii. Improve cardiovascular system: Animal experiments and clinical trials have shown that ganoderma lucidum can effectively dilate coronary arteries, increase coronary blood flow, improve myocardial microcirculation, and enhance myocardial oxygen and energy supply. Therefore, ganoderma lucidum has a protective effect on myocardial ischemia, and can be widely used in the treatment and prevention of coronary heart disease and angina pectoris. For patients with hyperlipidemia, Ganoderma lucidum can significantly reduce blood cholesterol, lipoprotein and triglyceride, and can prevent the formation of atherosclerotic plaque. For atherosclerotic plaque has formed, it has the effect of reducing the cholesterol content of arterial wall, softening blood vessels and preventing further damage. It can also improve local microcirculation and prevent platelet aggregation. These effects have a good effect on prevention and treatment of various types of stroke.
iv. Skin whitening: In Compendium of Materia Medica, Li Shizhen pointed out that Ganoderma lucidum has "increased wisdom and good color". Ganoderma lucidum is a kind of anti-wrinkle, anti-inflammatory, discoloration and skin protection. Ganoderma lucidum contains components that inhibit melanin and a variety of trace elements that are beneficial to the skin. These components can accelerate the regeneration of cells by reducing free radicals in the human body, increasing the thickness of the skin and increasing collagen, so as to achieve the effect of enriching the skin and eliminating fine lines and wrinkles. Its polysaccharides can restore skin elasticity and make skin moist and delicate by maintaining and regulating skin water quality.
i. The effect on the central nervous system: Ganoderma lucidum tincture, Ganoderma lucidum fermented concentrated liquid, mycelium alcohol extract and alcohol extract after defatting sporangium powder can reduce the spontaneous activity of mice by intraperitoneal injection.
ii. Effects on the cardiovascular system: ganoderma lucidum tincture effect on in vitro toad heart has a strong heart, intraperitoneal injection of rabbit included tincture can make heart contraction force to strengthen, the heart rate change is not big, intraperitoneal injection of ganoderma lucidum alcohol extract, rabbit caused by pituitrin T wave high significant protection against the electrocardiogram, and suggests that it's a confrontation of acute myocardial ischemia.
iii. Anti-platelet aggregation and anti-thrombotic effect: Ganoderma lucidum injection has a significant inhibitory effect on ADP and collagen-induced platelet aggregation in vitro. Healthy people who take 0.2g of Ganoderma lucidum daily for a week also have a significant inhibitory effect on ADP-induced platelet aggregation, but the effect on collagen-induced platelet aggregation is poor. Taking Ganoderma lucidum for 2 weeks in patients with myocardial infarction or cerebral infarction can inhibit ADP-induced platelet aggregation in both in vivo and in vitro, and it also has a significant inhibitory effect on thrombosis in vitro.
iv. Effects on respiratory system: phenol red excretion experiment in mouse trachea proved that alcohol extract of Ganoderma lucidum and Ganoderma sp. Fermentation liquid intraperitoneal injection has the effect of expectorant.
v. Effects on metabolism and endocrine function: Intraperitoneal injection of ganoderma lucidum polysaccharide BN3C (i.e. D6) in mice can promote the synthesis of protein and nucleic acid in serum, liver and bone marrow, accelerate the division and proliferation of bone marrow cells, increase the content of P-450 in liver homogenate cells, and improve the detoxification function of liver. Ganoderma lucidum extract can increase plasma cortisol content in scald animals.
vi. Hepatoprotective effect: Ganoderma lucidum tincture can reduce liver damage caused by carbon tetrachloride poisoning in mice.
vii. The effect of Ganoderma lucidum injection on experimental myotonia induced by 2, 4-trichlorophenoxyacetic acid can significantly reduce ALdolase in mice.
viii. Antioxidant and anti-aging effects: Ganoderma lucidum polysaccharides GLA, GLB and GLC have inhibitory effects on the production of superoxide anion (O) free radicals and red blood cell lipid peroxidation, and have scavenging effects on hydroxyl free radicals (•OH), and have superoxide dismutase like activity, which is an important factor for delaying aging of Ganoderma lucidum.
ix. Anti-inflammatory effect: Both artificial and natural ganoderma lucidum water-decocted liquor concentration can significantly inhibit carrageenan-induced joint swelling in rats.
x. Anti-tumor effect: The crude extract of Ganoderma lucidum fruiting stalk inhibited mouse S180 by 87.6%, and its components contained polysaccharide and protein. A variety of polysaccharides isolated from the hot water extract of Ganoderma lucidum have inhibitory effect on S180 transplanted tumor in mice by intraperitoneal injection. Oral administration is ineffective.
xi. Immune regulation: ganoderma lucidum polysaccharide separation of proteins in the abdominal cavity injection can make the mouse peritoneal exudate cells, macrophages and polymorphonuclear leucocyte increased, that has immune strengthening effect, immune to sheep red blood cells (SRBC) in mice spleen hemolytic plaque forming cells was significantly increased, the polysaccharide containing galactose, glucose and xylose.
Ganoderma lucidum is bitter, but bitter and fragrant. Ganoderma lucidum is valuable because it contains rich polysaccharides and three posts, wild ganoderma lucidum is also rich in many such as trace elements; After extraction without destroying the natural activity of ganoderma lucidum, most of the essence contained in it can be released, thus being absorbed and utilized by the human body. Ganoderma lucidum can be eaten in the following ways:
i. Ganoderma ganoderma drink: take ganoderma ganoderma (whole ganoderma ganoderma) slices, add water, put in a gentle fire and simmer for 2 hours, take the juice and add honey to drink.
ii. Ganoderma lucidum water decocting method: the ganoderma lucidum slice, into the pot, add water decocting, generally decocting 3-4 times. Mix all the decoction and take it orally in small doses.
iii. Ganoderma ganoderma bubble wine: cut Ganoderma ganoderma ganoderma into the bottle of liquor sealed soak, after 3 days, when liquor becomes brown red can drink, still can join rock sugar or honey.
