Hawthorn Berry Extract

Hawthorn Berry Extract Powder Description

Hawthorn extract is a brown-yellow powder extracted from the dried and mature fruits of the Rosaceae plant CrataeguspinnatifidaBge.var.majorN.E.Br. or Hawthorn Crataeguspinnatifida Bge. The main active ingredients are various organic acids. It has the functions of digestion and stomach strengthening, anti-inflammatory and anti-cough, lowering blood pressure, lowering blood lipid, increasing coronary blood flow, preventing coronary heart disease and angina pectoris, and anti-cancer and anti-cancer effects. RealclearBio also accept customization for Extract Ingredient, Content, Color, Solubility, Moisture, Ash, Heavy Metal, Pesticide Residue, Microorganism etc.

Molecular Formula: C₃₀H₄₈O₄ 

Molecular Mass: 472.6997

CAS No.: 4373-41-5

Constitutional Formula:

 Testing Index of Hawthorn Berry Extract

Hawthorn Berry Extract Package and Delivery

Our advantage on producing Hawthorn Berry Extract:

I. Raw material control for Hawthorn Berry:

1) Select high quality raw materials.

2) Strictly control the quality of raw materials: inspection of bulk samples before entering the factory -- random inspection of batches at the time of entering the factory.Ensure no mildew, reasonable control of impurities, absolute content in a controlled range.

Character identification： 

The fruit is a round slice, with many curled edges, and uneven, with a diameter of 1 to 2.5 cm and a thickness of 0.2 to 0.4 cm. The outer skin is red to dark red, with fine wrinkles and small gray-white spots. The flesh is dark yellow to light brown. The middle section has 5 light yellow pits, but the pits are mostly absent and hollow. Short and thin fruit stalks or calyx remnants can be seen on some slices.

Slightly fragrant, sour and sweet. The ones with large slices, red skin and thick flesh are better.

Microscopic identification

 1. Cross section (1) Cross section of Shanli red fruit, with 1 row of outer pericarp cells, similar to square, outer cuticle, and reddish brown inside. The mesocarp is extremely thick. There are 1-2 rows of brown pigment in the outer parenchyma cells, and the inner parenchyma cells contain starch granules and calcium oxalate square crystals and cluster crystals, with scattered vascular bundles.

(2) The cross-sectional characteristics of hawthorn fruit are similar to those of Shanlihong. The main difference is that most of the pale yellow, round stone cells are scattered in the parenchyma of the mesocarp.

2. Powder (1) Shanlihong powder: dark brown, sour and slightly sweet.

① There are many stone cells, round, oblong, polygonal, triangular or irregular, some with protruding edges or sharp ends, 18-173μm in diameter and 185μm in length, the larger ones are the majority, the wall poles

It is about 53μm thick, with obvious stratification, and there are often 1 to 3 circles of cracks on the wall.

The pores and grooves are thick and bifurcated, and some cells contain brownish-yellow secretions; smaller stone cells are sometimes arranged in rows.

② Calcium oxalate square crystals (13～52μm in diameter, 4μm in the smaller one) and calcium oxalate cluster crystals (27～41μm in diameter) are scattered or embedded in the pulp cells.

③The fiber Chemicalbook is bundled, and the upper and lower layers are arranged alternately, long fusiform, some ends are blunt and round, and the wall is extremely thick.

In addition, there are pulp parenchyma and skin cell fragments.

(2) The main difference between hawthorn and hawthorn is: small stone cells, 25-92μm in diameter, 176μm in length, thinner wall, rounded edges, no sharp end, and dense pores and grooves.

Physical and chemical identification Take the ethanol (95%) leaching solution of the powder, filter it, add a few drops of magnesium powder and concentrated hydrochloric acid to the filtrate, and it will be pink;

The medicine showed green fluorescence.

Ultraviolet spectroscopy identification Take 4 samples of 1g coarse powder (20-40 mesh) of the sample, put them in 50ml iodine measuring flasks, add petroleum ether (60～90℃), chloroform, absolute ethanol and 20ml of distilled water, and soak for 2h at room temperature , Shake, filter, the filtrate is appropriately diluted with the corresponding solvent, and the UV spectrum is measured on the Shimadzu UV-3000 UV spectrophotometer.

Test conditions: wavelength range 190～400nm, absorbance range 0～3A, slit 1nm, scanning speed 200nm/min, scale expansion 20nm/cm.

Results Haw λmaxPet was 217.0, 252.0, 258.0, 262.5, 294.0(sh), 306.0(sh)nm, λmaxCHCl3 was 263.0, 325.5(sh)nm, λmaxEtOH was 215.0, 274.5nm, λmaxH2O was 210.0, 278.0nm.

1. Petroleum ether immersion liquid 2. Chloroform immersion liquid 3. Absolute ethanol immersion liquid 4. Water immersion liquid

II. Production Control Hawthorn Berry Extract:

 1) Whole pollution-free pipeline input to ensure that the production process is rigorous, clean and qualified for microorganisms.

2) To ensure complete, accurate and traceable sampling detection for each process in the production process.

3) Ensure that the whole process of powder collecting and packaging is completed in an orderly manner in the Cleaning Area without foreign body invasion.

III. Quality Control for Hawthorn Berry Extract:

1) Ensure the cleanness of the mixing program.

2) Ensure the accuracy of finished product testing.

3) If the finished products are not qualified, the previous process shall be traced immediately.

4) Guarantee that the unqualified products will not be put into storage or leave the factory.

Iv. Service Control

1) Guarantee 20-50 grams of free pre-shipment sample testing to customers.

2) Follow up the customer's detection of samples and problems found until the problems are solved.

3) Complete all customer requirements and related documents for products.

4) Customize product color, content, packaging, labeling and transportation according to customer requirements.

5) Customers' feedback on product problems shall be guaranteed to give positive and effective response within 24 hours.