English  |
Grade: Food Grade
Certificates: Kosher/ HALAL
Supply Ability: 5 Tons/month
Sample: Free Sample 5-20g
Shelf Life: 2 years
Storage: Store in cool and dry place
Package: 1kg/bag, 25kg/paper drum
Delivery Method: DHL/ FedEx/ By air/ By sea
Payment Method：T/T, L/C, PayPal
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Chondroitin sulfate (CS) is a type of glycosaminoglycan that is covalently
linked to proteins to form proteoglycans. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues. The sugar chain is polymerized by alternating glucuronic acid and N-acetylgalactosamine, and is connected to the serine residue of the core protein through a sugar-like linking region.
Although the main chain structure of polysaccharides is not complicated, it presents a high degree of inhomogeneity in terms of the degree of sulfation, sulfate groups, and the distribution of the two differences into the chain of isomerized uronic acid. The fine structure of chondroitin sulfate determines the specificity of function and the interaction with a variety of protein molecules.
Cartilage nutrient is a white powder. It has good water absorption and is acidic mucopolysaccharide. It is mainly used in arthritis, eye drops, etc. It has the effects of relieving pain and promoting cartilage regeneration. It is effective in improving senile degenerative arthritis. Rheumatoid arthritis has a certain effect and can improve joint problems.
roduct Description | |
Product Name: | Chondroitin Sulfate |
English Alias： | Chondroitinsulfates poly-1(2/3)-n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4-(6)sulfonyl-d-galactose chonsurid chondroitinsulfuricacids chondroitinpolysulfate chondroitinsulfuricacid |
Appearance: | Off-White to White Powder |
Source: | Cartilage of shark, cow, pig, chicken |
Ingredient&Content: | 85%, 90%, 95%, 98% |
Test Method: | HPLC |
Extraction Type: | Solvent Extraction |
Customization: | Acceptable |
Function: | ※Adjust the functions of the body ※Waterway for supplying nutrients ※Maintenance of micronutrients ※Participate in making bones ※Early healing of the wound ※Keep joints smooth |
Application: | ※Dietary Supplements ※Health Care Products ※Food and Beverage Ingredients. ※Cosmetics ※Eyedrops |
Molecular Formula: C13H21NO15S
Molecular Mass: 463.36854
CAS No.: 9007-28-7
EINECS号：232-696-9
Constitutional Formula:
Chondroitin sulfate has high nutritional value and is very suitable for the elderly who need calcium supplementation.
It can effectively repair cartilage and increase bone density, thereby reducing the probability of fracture, preventing joint pain, and delaying the occurrence of osteoporosis.
Joint diseases are often related to excessive use of joints and carelessness in daily maintenance.
To maintain joints, we must first change the unscientific usage habits of joints. At the same time, supplement the joint nutrition cartilage collagen peptides to improve joints and cartilage, make the joints healthier, and effectively avoid various joint-related diseases and enjoy life better.
Extraction, enzymatic hydrolysis, precipitation, drying Weigh pig throat and nasal cartilage, soak in 5 times the amount of 20g/L (2%) sodium hydroxide solution, stir intermittently, when the extract reaches 5.5°Be, filter, and then extract the filter residue Once, combine the filtrate.
Hydrolyze with crude trypsin at 50℃ to remove impurities such as protein, filter to clear, adjust pH6, add ethanol to make the alcohol content 75%, and let it stand overnight. After centrifugal separation, the precipitate was washed with absolute ethanol and dried at 60°C to obtain crude chondroitin sulfate. Pig throat and nasal cartilage [20g/L NaOH]→Extract solution [Panzyme]→Enzymolysis solution→[pH6] Crude product fractionation Take 1kg of crude product and add 20L of distilled water, 1L of acetic acid and 500g of calcium chloride (calculated as anhydrous) In the mixed solution, stir until it is completely dissolved, and then add the volume fraction of ethanol to 50%, and there will be precipitation, and let it stand overnight.
Centrifuge to collect calcium salt precipitate. Re-dissolve it in a mixture of 40L of distilled water, 1.5L of acetic acid and 100g of calcium chloride (calculated as anhydrous), stir to dissolve, add ethanol to a volume fraction of 29%, precipitate and separate by centrifugation (recovery of CSA-Ca by precipitation). In the supernatant ethanol solution, continue to add an appropriate amount of ethanol, stir to make it white and permanent turbidity, and let it stand overnight.
The next day, add appropriate amount of ethanol to make the concentration reach 39%, and leave to precipitate and crystallize for 7 days. After centrifugation, the precipitate was washed with absolute ethanol and dried at 60°C to obtain CSA-Ca. CSA-Ca was recovered from the supernatant ethanol solution. Crude product [water, HAc, CaCl2, ethanol]→CSA-Ca transformation, precipitation, drying Take the pure CSA-Ca product and dissolve it with a proper amount of distilled water, adjust the pH to 7, and then adsorb on the strong acid styrene cation exchange resin 001×7, and collect the effluent, Add 5g/L (0.5%) of sodium chloride solution volume, precipitate with ethanol, and let stand overnight. After centrifugation, the precipitate was washed twice with absolute ethanol and dried at 60°C to obtain pure sodium chondroitin sulfate A. The total yield is calculated as 5% for pig throat and nasal cartilage. CSA-Ca[001×7 resin (Na type)→[pH7] effluent (CSA-Na)[NaCl, ethanol]→precipitate→CSA-Na pure product.
How to supplement chondroitin sulfate?
Peptide Good Life Cartilage Collagen Peptide, the main components of which are chondroitin sulfate, type II collagen, and hyaluronic acid, help to promote the repair of human cartilage, prevent cartilage friction and wear, and smooth joint movement. Improve joint pain, knee weakness, cartilage repair, osteoporosis, loss of joint flexibility, anti-inflammatory and pain relief, and promote calcium absorption.
With age, the regeneration ability of joint fluid in cartilage decreases, and the synthesis speed cannot catch up with the decomposition speed. Therefore, it is recommended to actively supplement hyaluronic acid. The skin and internal organs of mammals are rich in hyaluronic acid.
In addition, it can also be ingested from foods such as shark fin, bird's nest, chicken wings, etc., but it should be noted that hyaluronic acid is not resistant to high temperatures, so a large amount of content is lost, and the hyaluronic acid in food has large molecules and is difficult to digest and absorb. Ingest large amounts or excessive intake of other ingredients, such as fat, lactose, and protein. Small molecules of cartilage collagen peptides are more suitable for human absorption.
Particle Size: | NLT 100% 80mesh |
Odor: | Characteristic |
Taste: | Characteristic |
Moisture: | 5%max |
Ash: | 5%max |
Heavy metal: | 10ppm max |
Pesticides: | Negative |
Total Plate Count: | 1000cfu/g max |
Yeast / Mold: | 100cfu/g max |
E. Coli: | Negative |
Salmonella: | Negative |
By Express | By Air | By Sea |
Suitable for under 50kg | Suitable for more than 50kg | Suitable for more than 500kg |
Fast: 3-7 days | Fast: 3-7 days | Slow: 7-45 days |
Hight Cost | Hight Cost | Low Cost |
Door to door service | Port to port | Port to port |
Easy to pick up the goods | Professional broker needed | Professional broker needed |
I. Raw material control:
1) Select high quality raw materials.
2) Strictly control the quality of raw materials: inspection of bulk samples before entering the factory -- random inspection of batches at the time of entering the factory.Ensure no mildew, reasonable control of impurities, absolute content in a controlled range.
II. Production Control Chondroitin Sulfate:
1) Whole pollution-free pipeline input to ensure that the production process is rigorous, clean and qualified for microorganisms.
2) To ensure complete, accurate and traceable sampling detection for each process in the production process.
3) Ensure that the whole process of powder collecting and packaging is completed in an orderly manner in the Cleaning Area without foreign body invasion.
|
|
III. Quality Control for Chondroitin Sulfate:
1) Ensure the cleanness of the mixing program.
2) Ensure the accuracy of finished product testing.
3) If the finished products are not qualified, the previous process shall be traced immediately.
4) Guarantee that the unqualified products will not be put into storage or leave the factory.
Iv. Service Control
1) Guarantee 20-50 grams of free pre-shipment sample testing to customers.
2) Follow up the customer's detection of samples and problems found until the problems are solved.
3) Complete all customer requirements and related documents for products.
4) Customize product color, content, packaging, labeling and transportation according to customer requirements.
5) Customers' feedback on product problems shall be guaranteed to give positive and effective response within 24 hours.
Chondroitin sulfate (CS) is a type of glycosaminoglycan that is covalently linked to proteins to form proteoglycans. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues. The sugar chain is polymerized by alternating glucuronic acid and N-acetylgalactosamine, and is connected to the serine residue of the core protein through a sugar-like linking region.
Although the main chain structure of polysaccharides is not complicated, it presents a high degree of inhomogeneity in terms of the degree of sulfation, sulfate groups, and the distribution of the two differences into the chain of isomerized uronic acid. The fine structure of chondroitin sulfate determines the specificity of function and the interaction with a variety of protein molecules.
Cartilage nutrient is a white powder. It has good water absorption and is acidic mucopolysaccharide. It is mainly used in arthritis, eye drops, etc. It has the effects of relieving pain and promoting cartilage regeneration. It is effective in improving senile degenerative arthritis. Rheumatoid arthritis has a certain effect and can improve joint problems.
roduct Description | |
Product Name: | Chondroitin Sulfate |
English Alias： | Chondroitinsulfates poly-1(2/3)-n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4-(6)sulfonyl-d-galactose chonsurid chondroitinsulfuricacids chondroitinpolysulfate chondroitinsulfuricacid |
Appearance: | Off-White to White Powder |
Source: | Cartilage of shark, cow, pig, chicken |
Ingredient&Content: | 85%, 90%, 95%, 98% |
Test Method: | HPLC |
Extraction Type: | Solvent Extraction |
Customization: | Acceptable |
Function: | ※Adjust the functions of the body ※Waterway for supplying nutrients ※Maintenance of micronutrients ※Participate in making bones ※Early healing of the wound ※Keep joints smooth |
Application: | ※Dietary Supplements ※Health Care Products ※Food and Beverage Ingredients. ※Cosmetics ※Eyedrops |
Molecular Formula: C13H21NO15S
Molecular Mass: 463.36854
CAS No.: 9007-28-7
EINECS号：232-696-9
Constitutional Formula:
Chondroitin sulfate has high nutritional value and is very suitable for the elderly who need calcium supplementation.
It can effectively repair cartilage and increase bone density, thereby reducing the probability of fracture, preventing joint pain, and delaying the occurrence of osteoporosis.
Joint diseases are often related to excessive use of joints and carelessness in daily maintenance.
To maintain joints, we must first change the unscientific usage habits of joints. At the same time, supplement the joint nutrition cartilage collagen peptides to improve joints and cartilage, make the joints healthier, and effectively avoid various joint-related diseases and enjoy life better.
Extraction, enzymatic hydrolysis, precipitation, drying Weigh pig throat and nasal cartilage, soak in 5 times the amount of 20g/L (2%) sodium hydroxide solution, stir intermittently, when the extract reaches 5.5°Be, filter, and then extract the filter residue Once, combine the filtrate.
Hydrolyze with crude trypsin at 50℃ to remove impurities such as protein, filter to clear, adjust pH6, add ethanol to make the alcohol content 75%, and let it stand overnight. After centrifugal separation, the precipitate was washed with absolute ethanol and dried at 60°C to obtain crude chondroitin sulfate. Pig throat and nasal cartilage [20g/L NaOH]→Extract solution [Panzyme]→Enzymolysis solution→[pH6] Crude product fractionation Take 1kg of crude product and add 20L of distilled water, 1L of acetic acid and 500g of calcium chloride (calculated as anhydrous) In the mixed solution, stir until it is completely dissolved, and then add the volume fraction of ethanol to 50%, and there will be precipitation, and let it stand overnight.
Centrifuge to collect calcium salt precipitate. Re-dissolve it in a mixture of 40L of distilled water, 1.5L of acetic acid and 100g of calcium chloride (calculated as anhydrous), stir to dissolve, add ethanol to a volume fraction of 29%, precipitate and separate by centrifugation (recovery of CSA-Ca by precipitation). In the supernatant ethanol solution, continue to add an appropriate amount of ethanol, stir to make it white and permanent turbidity, and let it stand overnight.
The next day, add appropriate amount of ethanol to make the concentration reach 39%, and leave to precipitate and crystallize for 7 days. After centrifugation, the precipitate was washed with absolute ethanol and dried at 60°C to obtain CSA-Ca. CSA-Ca was recovered from the supernatant ethanol solution. Crude product [water, HAc, CaCl2, ethanol]→CSA-Ca transformation, precipitation, drying Take the pure CSA-Ca product and dissolve it with a proper amount of distilled water, adjust the pH to 7, and then adsorb on the strong acid styrene cation exchange resin 001×7, and collect the effluent, Add 5g/L (0.5%) of sodium chloride solution volume, precipitate with ethanol, and let stand overnight. After centrifugation, the precipitate was washed twice with absolute ethanol and dried at 60°C to obtain pure sodium chondroitin sulfate A. The total yield is calculated as 5% for pig throat and nasal cartilage. CSA-Ca[001×7 resin (Na type)→[pH7] effluent (CSA-Na)[NaCl, ethanol]→precipitate→CSA-Na pure product.
How to supplement chondroitin sulfate?
Peptide Good Life Cartilage Collagen Peptide, the main components of which are chondroitin sulfate, type II collagen, and hyaluronic acid, help to promote the repair of human cartilage, prevent cartilage friction and wear, and smooth joint movement. Improve joint pain, knee weakness, cartilage repair, osteoporosis, loss of joint flexibility, anti-inflammatory and pain relief, and promote calcium absorption.
With age, the regeneration ability of joint fluid in cartilage decreases, and the synthesis speed cannot catch up with the decomposition speed. Therefore, it is recommended to actively supplement hyaluronic acid. The skin and internal organs of mammals are rich in hyaluronic acid.
In addition, it can also be ingested from foods such as shark fin, bird's nest, chicken wings, etc., but it should be noted that hyaluronic acid is not resistant to high temperatures, so a large amount of content is lost, and the hyaluronic acid in food has large molecules and is difficult to digest and absorb. Ingest large amounts or excessive intake of other ingredients, such as fat, lactose, and protein. Small molecules of cartilage collagen peptides are more suitable for human absorption.
Particle Size: | NLT 100% 80mesh |
Odor: | Characteristic |
Taste: | Characteristic |
Moisture: | 5%max |
Ash: | 5%max |
Heavy metal: | 10ppm max |
Pesticides: | Negative |
Total Plate Count: | 1000cfu/g max |
Yeast / Mold: | 100cfu/g max |
E. Coli: | Negative |
Salmonella: | Negative |
By Express | By Air | By Sea |
Suitable for under 50kg | Suitable for more than 50kg | Suitable for more than 500kg |
Fast: 3-7 days | Fast: 3-7 days | Slow: 7-45 days |
Hight Cost | Hight Cost | Low Cost |
Door to door service | Port to port | Port to port |
Easy to pick up the goods | Professional broker needed | Professional broker needed |
I. Raw material control:
1) Select high quality raw materials.
2) Strictly control the quality of raw materials: inspection of bulk samples before entering the factory -- random inspection of batches at the time of entering the factory.Ensure no mildew, reasonable control of impurities, absolute content in a controlled range.
II. Production Control Chondroitin Sulfate:
1) Whole pollution-free pipeline input to ensure that the production process is rigorous, clean and qualified for microorganisms.
2) To ensure complete, accurate and traceable sampling detection for each process in the production process.
3) Ensure that the whole process of powder collecting and packaging is completed in an orderly manner in the Cleaning Area without foreign body invasion.
|
|
III. Quality Control for Chondroitin Sulfate:
1) Ensure the cleanness of the mixing program.
2) Ensure the accuracy of finished product testing.
3) If the finished products are not qualified, the previous process shall be traced immediately.
4) Guarantee that the unqualified products will not be put into storage or leave the factory.
Iv. Service Control
1) Guarantee 20-50 grams of free pre-shipment sample testing to customers.
2) Follow up the customer's detection of samples and problems found until the problems are solved.
3) Complete all customer requirements and related documents for products.
4) Customize product color, content, packaging, labeling and transportation according to customer requirements.
5) Customers' feedback on product problems shall be guaranteed to give positive and effective response within 24 hours.
